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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e290f78b4021964aed181a309443e8c718904b41ce2df19883a456234bf3bbcc' 
  AND token = 'GLYcTMNw4vLzMNJVD8sf7pJU0A1Jnp1hkzF2dGY1s2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}