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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1e59ba2b5b58be2f1387aa38efcf2c539fa39ff4ae447d50911d7e47504a29' 
  AND token = 'VjayH6nNay1Eq23ttZXs2RCk+20j02ebocMHXr2XtSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}