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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aadcca75bb77bf3b3916644d1dcea86e32b475eee9e258201d4553b47d5c0340' 
  AND token = 'r6dEmSsvKa3/cjJ9lhwuaJFanaaD7EOXc36xlEUnnsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}