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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3647d0ee95f257cef9ab596492771afc2205ecaa6ea2231a76ab542de64ddf' 
  AND token = 'aq+g5zTBstRS6M+ZpgagOb/nEmm47r5lpdCPHJzzsb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}