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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c31e311a77f9cd518e1ea0d78a7394d806f9c63e8e46e15e359cca457e576a' 
  AND token = 'Uf0ZE6NkxzA6Ah/a8x7MZBuhFnPP1JCQrywNKf+tVTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}