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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ec8aa1b36b8900d087f45cb7f960798b850b12665e86e44c5499e2c05c0db5' 
  AND token = 'z7DQccOQJFGz2iJNGXz3bmgM4ilQNs1o9zKxXu2Y0Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}