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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605f147d1e932aa0121beea5de3d536c8bc98a360210bd6bc28ce710ac16a042' 
  AND token = '6u3HT341Iiq2efqaZJEkwcLl0yn4hcv/KJLsGv2nZaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}