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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432c3f7b0fe4a0b3bdfd149288f3a1845b64fd04534580800769dfb7d1a7b53e' 
  AND token = 'hyAdFjh/Dd5D2LLfVIEXQ+Q9soX1HsB0FuqjChatBTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}