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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c04586567810d772c230e1fdfd161b113bfc58c61b0b6e777a913b009664a376' 
  AND token = 'na+lyjFcL37AtlV01gVcMXXHUmB7DgCVzD/JHRiwJLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}