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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10116a6fe8668370dd19e740bac6eca741a655e11d284b0b25082b7d9e77da20' 
  AND token = 'cfcrykMfHSV1Boz653iZXzPwp/RkeRWCOTSTAieKxFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}