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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52035b77f86b0dd8db693ccd90db7d7526b8464d27e86b5ffe8b2b95d67c182' 
  AND token = 'TiTzy6jmL1hbEjDzGFOf8u56ieOShFkwh72TO3OgdO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}