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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6d57aca063b6c0fc9353a94ca31fe184227e4248a6cb8116dfa202b768a337' 
  AND token = 'bQU0uFXLg2EAX+4YRCHm8W4DNeEZCigtUdq4MJf60OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}