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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3acc73e39b4cbd07bfc498c3a66c53f6a2680603ee20585eeb843f44f940dd2d' 
  AND token = 'MR7tszZ9vE2ON9JGnsx222ggA8FyoCMonk6sRCpv2fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}