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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a8a860386c18e3edda78516a13c32b6978e5ad015a139f50f5724fe242a824' 
  AND token = 'eOpolSw5dWT5uiY9eB9MDiA0nRfEj67uF/7Bw5fHINY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}