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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133c7dc91e6f13c253843c7da3949653f026b0277661539f2b28f6292400f9da' 
  AND token = 'L7HWv0ANlxj/yosrWR2fhdQvtlJfZ2UXVrLPSB04Ip8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}