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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '547a37a5b5c374cc23d1a865c251a1e6ba4a2e957ec0efaeb7931b3d1284fe31' 
  AND token = 'Rw7OcKhiaTSWUwD4ngmj+6wOnxymwMo/V2V5wT0ScLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}