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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653225948bbe349c322424946a702b87ff5605ceb8b97b953c03da5a6eaf1da4' 
  AND token = 'sH+Gjh2Yjye0ZVE2K9kp9dYrevzc3W06FRrvLpTrOrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}