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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80cf40ad6d70c08fbb01b0e8f023b2a4df878d93df523f311f1e55971ed1d09' 
  AND token = 'AwJ/nO6SJJFio6FDU5svH5vchqVyjHvdCrBl2z9eCD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}