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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc167e15132d3971dd522009c4ee857b29d43aac6edd18b460951fd84553ef55' 
  AND token = '+HS8p2+yRG2Brc+n02nRGNc+GefsDr+EE1lN4Ps0XiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}