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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0dd45abcb94706b2b3624559d3d46caa81ce3d621626718a9f3e64ede1ff20b' 
  AND token = 'SMu8WtmSgKqRknrSnIToL+h2XrID0PqVFHX5GDbRukw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}