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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522f8dff2372dae21d140930e7b451f28f6d1b617ac264a2fa9fdff8c9e41665' 
  AND token = 'jt5Cgr6EMiro+L7989gFRk0VctdsqbKcd7xcgn8qMWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}