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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d332662c659800ffa5f6ffe355afcc89f67e33753c88f4c8a5b348260fc0932' 
  AND token = 'AEJF21XCpsXkD9R2L6NNXM35JenG7G23ykMSg4k8etw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}