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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c779925686884d230b7fbf584175b53db4ef2def5b5ab8e0ee7c23d2d2ff5b9c' 
  AND token = '3qwse2NxdUevUm3PZnXyCMrTFp9MmeonbhVOy2FUhXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}