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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe1727dc0288a1070b20d38ab43e37727ec5c75f178dd4aec98a4d5138d922c' 
  AND token = 'lWAohkwC6/9u6L0tHcY9zW9tRbQkTIJPrzaZ7b/G1EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}