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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7650c6efd9b2e15fc4be784eaf2ed7f68884292d0cc28f5127026b6d9b6928' 
  AND token = 'lwvYNlRQ/RSoFuRWZcQIRw309dAyBv9gDSjY1gXE8v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}