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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed179e65d7cb0825581671103730382a21e84b8c7b3d1fb5c520b9fe61d1c17' 
  AND token = 'LOfkmHCpSDSvinRC/ekqzd8YI49qxtNIw5Zo+zlY29I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}