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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '407f0c1c7a6e10675e61ee846296ebdeeec7d96dbf87b7f4e122f870c429a58c' 
  AND token = 'edBfBoXCNY/bJXSVd0sSM1iC1eV5KGM3FE+TMiRYXyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}