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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e804e7b4c7f9fe043b0fb84e526d0187d0d3eea35a285744e5450a3e37354788' 
  AND token = 'CQ+XLOnsC8uojszcmxI1ykCSW8nwCI3v9Z4cTkJWEQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}