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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb08c7bdcbc555d2a14a3e73248e01cf3d9318203bada099967d966df45fba3' 
  AND token = 'bDYmu8vbQn64Oa9SdTIK44/zsjCDn1ASvw7XMdlxW4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}