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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd36cea962b36360b639a121c99fe1d161342d8d648f3e3de8c135e9074d934f4' 
  AND token = 'Q3n4aconzgp7lJwzOmC5zfMnhX6krXb1Fh2Tz2+03rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}