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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3f7bcca6f455bdf80c5a9ba811e47f92b6e582e0a60ccb84f9e7ddb0748b05' 
  AND token = '0Sh3ZpZy5CwSWsh7tAD5wEQkXtu+4PfUfvrOAtDjo/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}