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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d7156b6128d060a9dceda78d746b4922b6d58bb2aa8bcc08ed76443e64e829' 
  AND token = 'h1aNoY4gzXM8lY9W+jgY9gg1Pkg+/ihz9HpBQpZfcBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}