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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ace50c9f025fadae6394e5a42304bbd40d026b94dadb149dbdf4cd45e73732d' 
  AND token = '8Hy6oAjTH0s6lAxfGXNkK2IO+3n1gJWXzlkcpZLlkj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}