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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c319fbd6ef44a76180bcdb9777c3b368810ce935369e29d9725134011f283db6' 
  AND token = 'QFzg30e7ogzQ/5hhEpYcZv3195kLyxM5je7jlG5YWvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}