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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a5f8f996370629f5b1d1ef50d8ba741ec82f21600a5f45ab2a91931a8f52cb3' 
  AND token = '8mHiDKKIIDLjTA3orat5IgBI+rkRHVDWmQCRX6Lxzjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}