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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344d03b82d6c4e3d73461422a613dc541f96756546fca1a329e58344541d9c30' 
  AND token = 'bWpy9Z2dmqaecSCED06wvH3Kpb/sDM3/cHeXSW5gs2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}