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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6db6db48d625a94b692e657c8ebd89cab4a3ab0988d4f178a0fc74635859f0' 
  AND token = 'C+3BG/8vpmkW9nI+HDfJK8XqZy93aeZS57/9JWS/rfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}