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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd382fee4c2f71a1fcee48b2c29112b2535e50b6744da5824228d7d9009ccc24' 
  AND token = 'xFSNuyJ5olam76bCL56R2GMk8L+2wIFoPS53MHcgU48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}