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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f278f9b1287b2c0b6e5fa7f17acf07e056c4bedda8369e89c3bb9fae0d31e45' 
  AND token = 'e5Yy0zNZt0asjcvyqe7toLu4C4hQa+ZuSdV78hu0Gz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}