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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469057a12c3ee7611b489f8f4028c9ee5bd7e6927ec9a723955f46cf8095c2ce' 
  AND token = 'O1cfPosRKgRxV+ecyeOVmcfK53WYo0l0EpDZqRiJIb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}