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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ac1b8e4b8b3ccb43656bec54236a9ca0d74fe2b84c0914a7e624eb91b9e6af' 
  AND token = '6RoiLPMeWp45Jt4E2JV0sYNr0cJlZONycsyTmqPgSwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}