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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f53cecb8e931ba62bbd3966a797a501b500b350775c7baaa2d1583c939f29af' 
  AND token = 'bsh0fKs1qKL+XaQKk4Kz6PSH7QlKtogvgKPbds3go90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}