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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42cc1d23e9c3d98c6b83d059ee15a238dcd2961b7cdeb53c3ccbfd513dbfd165' 
  AND token = 'P+/Sf/oNnHPh/oVmZKzEyZp1DdYgv1F43bpZ03JUC70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}