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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49046c9c48fa9a2c03815233cf37ef3b99f586fc3e2dd2ad8c69569e838ad303' 
  AND token = 'bWibKB3uhybZl/7wqUn27UubNz9/xQ1yWjuLA8TMMFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}