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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd2fd951cf18b46bc464744bfd7ca0b1c81ff8acd1d04cac637f861671bf36a' 
  AND token = 'EJ5/6MHJHw1cBtUdlcU6j/TAIIjeq0LPMQFxfMQNpIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}