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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a727e83bb782d5d05f711a09d686921a0f29312a307242927af7539ea050714' 
  AND token = '/ELeQ5T1G8wCLbqnuoENAWxfESm9rQ+YADpx8Wi6j6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}