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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e400426f85e05bdebdc21d9f2747a94a379fdaf51004196dc21eb12477757b4' 
  AND token = 'mswSP4tcHn9yNpNZiDO6xxvtH21awy1v0N92wUg2cTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}