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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fa57072f578aad4bc171eea08be7f059fb05d4f8307296e75ac4dcb1c932d4' 
  AND token = 'K3aXNwsU3P4axtb1hu7rVHrc/3ulqhB/eLTLHTrbUFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}