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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e04f3f9b88c54c6a690bd5cc284ce9825edaea92eeb576780c4990946e6b284' 
  AND token = 'VkwoIvO5mXProY+lfjBE4kj3U0rQ8JrW9LrBY9aMbcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}