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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b899e3cde4ec95375eb096efb0221860e4542a16f0878de3124a717b83f97b' 
  AND token = 'I93roZgCVl0zxi/g9xRel3yKqReb67YSddjZ51FzalA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}